Centro Universitario de los Altos

Resumen Derivado de los impactos ocasionados por la pandemia COVID-19 en el ámbito de las universidades durante los años 2020, 2021 e inicios de 2022, se expone el presente artículo como resultado de una investigación que tuvo por objetivo: explicar los efectos de la COVID-19 en el proceso de aprendizaje de estudiantes universitarios del Centro Universitario de los Altos de la Universidad de Guadalajara. El abordaje fue estructurado y siguió el método de investigación holopráxico, desde el q...

Background: Dental caries can affect the expression of salivary proteins. Proteomics allows us to analyze and identify many proteins in a single sample and experiment; bioinformatics is essential to analyze proteomic data. Objective: This research aims to identify and integrate the main differentially expressed proteins in the saliva of children with caries, infer their Gene Ontology and interactions, and identify regulatory factors. Materials and Methods: We extracted proteins from a b...

Head and neck tumor differential diagnosis and prognosis have always been a challenge for oral pathologists due to their similarities and complexity. Artificial intelligence novel applications can function as an auxiliary tool for the objective interpretation of histomorphological digital slides. In this review, we present digital histopathological image analysis applications in oral squamous cell carcinoma. A literature search was performed in PubMed MEDLINE with the following keywords: “art...

Abstract Background Bacterial multi-resistance is a serious global problem that continues to worsen over time due to multiple factors. Among these factors, it is important to highlight the clinical misuse of antibiotics and the mechanisms that microorganisms have developed to protect themselves from these drugs. In this sense, Staphylococcus aureus (S. aureus) is a pathogen that has found a way to resist many of the drugs currently in use, so infections by this bacterium represent a serious...

The objective of this systematic review and meta-analysis was to evaluate the analgesic efficacy of COX-2 inhibitors versus other drugs in periodontal surgery. Two researchers searched PubMed, Google Scholar, ACM Digital, BASE, EBSCOhost, Scopus, or Web of Science for clinical trials using various combinations of words. All articles that met the selection criteria were assessed using the Cochrane Collaboration’s risk of bias tool. For data analysis, the inverse variance and mean differen...

Periodontal disease is one of the most common inflammatory disorders in humans. Gingivitis is the mildest form of periodontal disease and its progression can lead to periodontitis, an inflammatory disease characterized by soft tissue damage that can lead to progressive destruction of the periodontal ligament and alveolar bone. Diverse populations of immune cells are involved in periodontal disease. Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous group of immature myeloid ce...

Abstract: Objective This study aimed to identify the molecular mechanism of curcumin on periodontitis based on a pharmacological network strategy. Methods The potential therapeutic targets of curcumin and differentially expressed genes in periodontitis were identified. Subsequently, we extracted the molecules in common and analyzed them. A metabolic pathway enrichment and gene ontology analysis were performed and the protein–protein interaction network was inferred. These analyses allowed ...

Abstract Background: The development and establishment of oral squamous cell carcinoma are confined to carcinogenesis, which involves oxidative stress via oxygen-free radical production as a hydroxyl radical (HO•), considered the most important cause of oxidative damage to basic biomolecules since it targets DNA strands. 8-Hydroxy-2´-deoxyguanosine (8-OHdG) is considered a free radical with a promutagenic capacity due to its ability to pair with adenosine instead of cytosine during replicati...

Neophytadiene (NPT) is a diterpene found in the methanolic extracts of Crataeva nurvala and Blumea lacera, plants reported with anxiolytic-like activity, sedative properties, and antidepressant-like actions; however, the contribution of neophytadiene to these effects is unknown. This study determined the neuropharmacological (anxiolytic-like, antidepressant-like, anticonvulsant, and sedative) effects of neophytadiene (0.1–10 mg/kg p.o.) and determined the mechanisms of action involved in the ...

Argemone ochroleuca Sweet (Papaveraceae) is used in folk medicine as a sedative and hypnotic agent. This study aimed to evaluate the anxiolytic-like, sedative, antidepressant-like, and anticonvulsant activities of a dichloromethane extract of A. ochroleuca stems (AOE), chemically standardized using gas chromatography–mass spectrometry (GC–MS), and its active compound dihydrosanguinarine (DHS). The anxiolytic-like, sedative, antidepressant-like, and anticonvulsant activities of the AOE (0.1–50...

Uno de los acontecimientos históricos mundiales que marcarán el futuro global en este pleno siglo XXI será, sin duda, la pandemia global del Covid-19. Este acontecimiento quedará en los anales de la historia como una huella indeleble para la posteridad de los seres humanos como un fenómeno de salud pública que marcó nuevas pautas para el manejo y uso de las relaciones humanas para evitar el contagio. Es por eso que en este escrito no podemos ni debemos pasar de largo el marco histórico mundia...

Es muy común que cuando se habla de crisis económica, se haga referencia a un problema concreto en alguna actividad productiva, una dificultad en cualesquiera de las variables macroeconómicas o a una serie de contradicciones que se viven en un sistema determinado. En realidad, todas estas apreciaciones tienen que ver, aunque sea de manera parcial, con el fenómeno de la crisis. Sin embargo, si en cualquier caso concreto, se puede dar solución a cualesquiera de estas valoraciones, se establece...

Studies report that increased body fat can lead to health risks for individuals. However, some methods used for analyzing adiposity did not identify its distribution in the human body because they are typically measured using bioimpedance scales. This study aims to associate the presence of cardiometabolic risk factors in sedentary and active adult populations through anthropometric methods based on skinfold thickness measurements. A cross-sectional study was conducted on 946 adults aged betw...

The effect on the physicochemical properties of aluminum salts on the synthesis of γ-AlOOH nanostructures has been investigated in detail using a hydrolysis-precipitation method. X-ray fluorescence (XRF), Fourier transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), field-emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM), were used to characterize the synthesized samples. The specific surface area, pore size distribution and pore diamet...

Physicochemical and sensory properties of Adobera, a genuine, understudied Mexican raw-milk cheese, were explored by analysing commercial samples from different manufacturers and seasons. Composition-wise, Adobera could be considered a fresh cheese with a high moisture content (42.5%), although its relatively low water activity (0.953) and pH (5.14) and high free amino acid content (0.46 mmol/g, dry basis) could indicate otherwise. Instrumental texture corresponded to that of a semifirm chees...

The objective was to study the behavior of the respiration rate (RR) of guamara and cocuixtle fruits during storage, the effect or the maturity stage (green maturity and consumption maturity) of these fruits on physicochemical parameters and specific proteolytic activity, as well as the antibacterial effect of the prepurified proteases of these fruits. The guamara and cocuixtle fruits presented a RR of 15 mL CO2/kg·h and 10 mL CO2/kg·h, respectively; and because the ethylene production was no...

Ultrasound-assisted extraction (UAE) is widely used; however, the efficiency of extraction depends on the raw materials. Therefore, optimization of UAE must be investigated for each type of plant material. By-products from soursop fruit have not been studied as a source of bioactive compounds. In this work, the optimization of UAE conditions (extraction time (5, 10, and 15 min), pulse cycle (0.4, 0.7, and 1 s), and sonication amplitude (40%, 70%, and 100%)) for the extraction of phenolic comp...

Home Bioactive Compounds in Underutilized Fruits and Nuts Living reference work entry Bioactive Compounds of Soursop (Annona muricata L.) Fruit Luis M. Anaya Esparza & Efigenia Montalvo-González Living reference work entry First Online: 01 October 2019 1015 Accesses Part of the Reference Series in Phytochemistry book series (RSP) Abstract Soursop (Annona muricata) belongs to the family Annonaceae and is widely distributed and commercially cultivated in the tropical and subtropi...

Mango is known as the king of the fruits; its nutritional importance, unique flavor, and delicious taste impart this status as super fruit. Furthermore, it is commercially cultivated in different tropical and subtropical areas in the world. Mangifera indica is the most important fruit of this genus; over 60 different species of edible mangoes are grown worldwide; however, the most of them are not marketable and underutilized and commonly are denominated as wild mango species, but they exhibit...