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Title: Innate and adaptive immunity of periodontal disease. From etiology to alveolar bone loss
Authors: Becerra Ruiz, Julieta Sarai
Guerrero Velázquez, Celia
Martínez Esquivias, Fernando
Martínez Pérez, Luz Andrea
Guzmán Flores, Juan Manuel
Keywords: bone loss
Issue Date: Apr-2021
Publisher: Wiley Online Library
Citation: Becerra‑Ruiz, JS, Guerrero‑Velázquez, C, Martínez-Esquivias, F, Martínez-Pérez, LA, Guzmán‑Flores, JM. Innate and adaptive immunity of periodontal disease. From etiology to alveolar bone loss. Oral Dis. 2021; 00: 1– 7.
Series/Report no.: Oral Diseases;2021;00:1–7.
Abstract: Abstract Periodontal disease refers to inflammation of the tissues that support the tooth. It is of multifactorial etiology. Innate and adaptive immune cells participate jointly through the release of their molecules and mechanisms of action in order to maintain homeostasis in periodontal tissues, so the host's immune response plays an essential role in defense against microorganisms. However, bacterial persistence and the dysregulation of the immune system as an exaggerated response can lead to the worsening of periodontal disease, leading to loss of gingival tissue and alveolar bone and thereby loss of teeth. Therefore, a better understanding of the cellular mechanisms involved in the development of periodontal disease is necessary to design new treatments and prophylactic measures in order to decrease the prevalence of this disease that afflicts a large part of the world population.
Description: Artículo
ISSN: 1601-0825
Appears in Collections:2412 Artículos

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