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Title: Recent Biomarkers for Monitoring the Systemic Fluoride Levels in Exposed Populations: A Systematic Review
Authors: Lavalle Carrasco, Jesús
Molina Frechero, Nelly
Nevárez Rascóon, Martina
Sánchez Pérez, Leonor
Hamdan Partida, Aida
González González, Rogelio
Cassi, Diana
Isiordia Espinoza, Mario Alberto
Bologna Molina, Ronell Eduardo
Keywords: fluoride biomarkers
recent biomarkers
Issue Date: Jan-2021
Publisher: MDPI
Citation: Lavalle-Carrasco, J.; Molina-Frechero, N.; Nevárez-Rascón, M.; Sánchez-Pérez, L.; Hamdan-Partida, A.; González-González, R.; Cassi, D.; Isiordia-Espinoza, M.A.; Bologna-Molina, R. Recent Biomarkers for Monitoring the Systemic Fluoride Levels in Exposed Populations: A Systematic Review. Int. J. Environ. Res. Public Health 2021, 18, 317. ijerph18010317
Series/Report no.: Int. J. Environ. Res. Public Health;2021, 18, 317
Abstract: Abstract: Fluorides are compounds that can be found in the minerals of soil with volcanic rocks. Different populations are exposed to high levels of fluorides through drinking water that, due to their chronic intake, cause several types of damage to health. Nails and hair, denominated as recent biomarkers, have been employed for monitoring systemic fluoride from long-term exposure to fluorides. The aim of this study was to perform a systematic review of the use of recent biomarkers for monitoring systemic fluoride levels in exposed populations and verify their validity in the measurement of the fluorine (F−) concentration within the body. A digital search was performed in the databases PubMed/Medline, Springer Link, Cochrane, and Scopus of original articles that employed recent biomarkers for monitoring systemic F−. Seventeen articles were included in this analysis; the recorded variables were the F− amount in each assessed biomarker, source of exposure, and total daily fluoride intake (TDFI). TDFI was associated with F− in nails and hair, as well as the exposure through drinking water. In conclusion, recent biomarkers are adequate for monitoring the systemic fluoride levels by evaluating the chronic/subchronic exposure through different sources, mainly drinking water, considering nails better than hair for this purpose.
Description: Artículo
ISSN: 1660-4601
Appears in Collections:3209 Artículos

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