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Title: Drug delivery system of green synthesized Ti-Cu nanocomposite
Authors: Martín Camacho, Ubaldo de Jesús
Torres Ramos, María Isabel
Sánchez Burgos, Jorge Alberto
Pérez Larios, Alejandro
Keywords: nanoparticles
green synthesis
drug release
Issue Date: Aug-2022
Publisher: Elsevier - Science Direct
Citation: U.J. Martín-Camacho, M.I. Torres-Ramos, J.A. Sánchez-Burgos, A. Pérez-Larios. (2022). Drug delivery system of green synthesized Ti-Cu nanocomposite, Materials Letters, Volume 321, 2022, 132437, ISSN 0167-577X, (
Series/Report no.: Materials Letters;Vol. 321, 15 August 2022, 132437
Abstract: Abstract: In this study, a drug delivery system was designed by the encapsulation of functionalized TiO2-Cu-Extract (TCE) nanoparticles obtained via green synthesis on a Poly(lactic-co-glycolic acid) (PLGA) matrix (TCE/PLGA). TCE nanoparticles showed improved optical absorption, band-gap energy, surface functional groups, and average nanoparticle size compared to pure TiO2 nanoparticles. The drug delivery system showed a controlled and sustained release for 24 h on simulated physiological conditions. β and n values of Weibull and Korsmeyer-Peppas models indicate that the release mechanism is a Fickian diffusion. Therefore, these results are promising for future research on the biomedical applications for TCE/PLGA drug delivery systems.
Description: Artículo
ISSN: 0167-577X
Appears in Collections:2414 Artículos

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