Please use this identifier to cite or link to this item:
Title: Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials
Authors: Montalvo González, Efigenia
Villagrán de la Mora, Blanca Zuamí
González Torres, Yesica Sughey
Iñiguez Muñoz, Laura Elena
Isiordia Espinoza, Mario Alberto
Ruvalcaba Gómez, José Martín
Arteaga Garibay, Ramón Ignacio
Acosta, José Luis
González Silva, Napoleón
Anaya Esparza, Luis Miguel
Keywords: hibiscus sabdariffa
clinical trials
health benefits
bioactive compounds
Issue Date: Apr-2022
Publisher: MDPI
Citation: Montalvo-González, E.; Villagrán, Z.; González-Torres, S.; Iñiguez-Muñoz, L.E.; Isiordia-Espinoza, M.A.; Ruvalcaba-Gómez, J.M.; Arteaga-Garibay, R.I.; Acosta, J.L.; González-Silva, N.; Anaya-Esparza, L.M. Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials. Pharmaceuticals 2022, 15, 464.
Series/Report no.: Pharmaceuticals;2022, 15 (4), 464
Abstract: Hibiscus sabdariffa Linn. Malvaceae (HS) is characterized by its edible calyxes. The HS calyxes are widely used for cosmetic, food, and medicinal applications. According to ethnobotanical evidence, decoction, infusion, or maceration extracts from HS calyxes have been used in folk medicine to treat many ailments. Moreover, several in vitro and in vivo studies have demonstrated the pharmacological properties and potential human health benefits of HS consumption. On the other hand, the evaluation of the physiological effects and health benefits of HS in clinical studies is most challenging. Therefore, this narrative review summarizes and discusses the physiological effects and health benefits of HS calyxes reported in clinical trials. Preparations obtained from HS calyxes (extracts, infusions, decoction, teas, beverages, capsules, and pills) are used as non-pharmacological therapies to prevent/control diverse chronic non-communicable diseases. The most-reported HS health benefits are its antihypertensive, antidyslipidemic, hypoglycemic, body fat mass reduction, nephroprotective, antianemic, antioxidant, anti-inflammatory, and anti-xerostomic activities; these effects are associated with the phytochemicals found in HS. Moreover, no adverse effects were reported during the clinical trials. However, clinical studies exhibited some limitations; thus, further studies are required to validate the clinical efficacy of HS in large-scale studies with higher doses and a good experimental design.
Description: Artículo
ISSN: 1424-8247
Appears in Collections:3201 Artículos

Files in This Item:
File Description SizeFormat 
Physiological Effects and Human Health Benefits.pdfDocumento1.61 MBAdobe PDFView/Open
Enlace a_Physiological Effects and Human Health Benefits.htmEnlace a publicación43.8 kBHTMLView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.