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Title: PLGA–TiO2 as a Carrier System for Drug Release
Authors: Torres Ramos, María Isabel
Martín Márquez, María Fernanda
Leal Moya, María del Carmen
Ghotekar, Suresh
Sánchez Burgos, Jorge Alberto
Pérez Larios, Alejandro
Keywords: TiO2 nanoparticles
drug delivery
Issue Date: Sep-2022
Publisher: MDPI
Citation: Torres-Ramos, M.I.; Martín-Marquez, M.F.; Leal-Moya, M.d.C.; Ghotekar, S.; Sánchez-Burgos, J.A.; Pérez-Larios, A. PLGA–TiO2 as a Carrier System for Drug Release. Int. J. Mol. Sci. 2022, 23, 10755. https://
Series/Report no.: Int. J. Mol. Sci.;2022, 23, 10755.
Abstract: Abstract This paper reports the results of the PLGA–TiO2 nanocomposite regarding the green synthesis of titanium dioxide nanoparticles using a natural extract, its characterization, and encapsulation with poly(lactic-co-glycolic acid) (PLGA). UV–visible spectrometry was used for the identification of terpenes present in the extracts. The morphology of the nanoparticles was determined by scanning electron microscopy. Infrared spectroscopy was used for the determination of functional groups, while X-ray diffraction was used to determine the crystal structure. The analysis of the extended release of the encapsulated extract in the matrix of the nanomaterial resulted in a maximum visible UV absorbance at approximately 260 nm and confirmed the synthesis of titanium dioxide nanoparticles. Moreover, terpenes enhance synthesis and stabilize titanium dioxide nanoparticles. The synthesized structures are spherical and amorphous, 44 nm in size, and encapsulated at 65 nm.
Description: Artículo
ISSN: 1422-0067
Appears in Collections:2414 Artículos

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